Discover how SETBP1 mutations disrupt protein degradation in atypical chronic myeloid leukemia, driving cancer progression through impaired ubiquitination.
Discover how a single detrimental mutation in the USP40 gene drives tumorigenesis in rare lung cancer cases through groundbreaking research.
Discover how the OPTN-K489E mutation disrupts cellular balance and accelerates ALS progression through enhanced apoptosis, necroptosis, and autophagy pathways.